FcRIreseptorin
FcRIreseptorin, also known as the high-affinity immunoglobulin E receptor, is a crucial component of the innate and adaptive immune system. It is a tetrameric transmembrane protein complex consisting of one alpha subunit, one beta subunit, and two gamma subunits. The alpha subunit is responsible for binding the Fc region of immunoglobulin E (IgE) antibodies, while the beta and gamma subunits are involved in signal transduction upon receptor activation.
This receptor is primarily expressed on the surface of mast cells and basophils, key effector cells in
The release of these mediators underlies the characteristic symptoms of allergic reactions, including inflammation, bronchoconstriction, and