DNAadduktioina
DNA adducts are covalent bonds formed between DNA and exogenous or endogenous compounds. These adducts can arise from various sources, including environmental pollutants, tobacco smoke, certain medications, and endogenous metabolites. DNA adducts can alter the structure and function of DNA, potentially leading to mutations, genomic instability, and increased risk of cancer.
The formation of DNA adducts is a critical step in the process of DNA damage. Once formed,
DNA adducts can be detected and quantified using various analytical techniques, such as high-performance liquid chromatography
The study of DNA adducts is of significant importance in the fields of toxicology, epidemiology, and cancer