Collectrin

Collectrin is a protein that plays a role in kidney function. It is a transmembrane protein, meaning it spans across a cell membrane. Collectrin is primarily found in the renal tubules, which are part of the nephrons in the kidneys. The main function of collectrin is related to the reabsorption of certain molecules in the kidney. It is involved in the transport of amino acids, specifically acting as a regulator for some amino acid transporters. By influencing these transporters, collectrin helps to ensure that essential amino acids are not lost in the urine and are returned to the bloodstream. Research suggests that collectrin may also be involved in other cellular processes beyond its direct role in amino acid transport, although these functions are less well understood. Mutations or alterations in collectrin have been linked to certain kidney diseases, highlighting its importance in maintaining kidney health. Further research is ongoing to fully elucidate the complete range of collectrin's functions and its precise involvement in various physiological and pathological conditions.