CSNK2A2

CSNK2A2, also known as casein kinase 2 alpha 2, is a gene that encodes a catalytic subunit of protein kinase CK2. This protein kinase is a highly conserved, ubiquitous serine/threonine kinase involved in a wide array of cellular processes. These include cell cycle progression, DNA repair, transcription, and signal transduction. The protein kinase CK2 exists as a heterotetrameric complex composed of two catalytic subunits (alpha or alpha prime) and two regulatory beta subunits. CSNK2A2 specifically encodes one of the alpha catalytic subunits. Dysregulation of CSNK2A2 has been implicated in various diseases, including cancer, where it can promote cell survival and proliferation. Mutations in CSNK2A2 have also been linked to certain developmental disorders. Research into CSNK2A2 and its role in cellular function continues to be an active area of study.

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