ACTR12s

ACTR12s refers to a class of proteins that are part of the dynactin complex. The dynactin complex is a multi-subunit protein assembly that is essential for the function of cytoplasmic dynein, a motor protein that transports cargo within cells. ACTR12s, also known as Arp11, is a highly conserved component of dynactin found in eukaryotes. It is thought to play a structural role within the dynactin complex, contributing to its overall stability and organization. Research suggests that ACTR12s is crucial for the proper assembly and function of dynactin, which in turn impacts various cellular processes. These processes include organelle transport, chromosome segregation during cell division, and cytoskeletal organization. Mutations or dysregulation of ACTR12s or the dynactin complex can lead to cellular dysfunction and have been implicated in certain neurological disorders. Understanding the precise role of ACTR12s is an ongoing area of research in cell biology.