leukotériákkal

Leukotériákkal, also known as leukotrienes, are a group of biologically active lipid mediators derived from arachidonic acid. They play a significant role in various physiological and pathological processes, particularly in inflammation and allergy. Leukotrienes are produced by the enzymatic action of leukotriene synthases, which are found in various cell types, including mast cells, basophils, and eosinophils.

There are five main types of leukotrienes: LTA4, LTB4, LTC4, LTD4, and LTE4. LTA4 is an unstable intermediate that can be converted into other leukotrienes. LTB4 is a potent chemotactic agent that attracts neutrophils to sites of inflammation. LTC4, LTD4, and LTE4 are cysteinyl leukotrienes that are involved in the regulation of smooth muscle contraction, vascular permeability, and bronchoconstriction.

Leukotrienes are involved in a wide range of physiological and pathological processes, including asthma, allergic rhinitis, and anaphylaxis. They are also implicated in the pathogenesis of other inflammatory diseases, such as rheumatoid arthritis and psoriasis. The regulation of leukotriene production and action is a major focus of research in the field of inflammation and allergy.