chemokinet
Chemokines are a class of small, low-molecular-weight proteins that play a crucial role in the immune system by acting as chemical messengers. They are involved in the recruitment of immune cells, such as leukocytes, to sites of infection or inflammation. Chemokines are classified into four main families based on their structure and function: CXC, CC, CX3C, and C. The CXC family, for example, includes chemokines like interleukin-8 (IL-8), which is a potent chemoattractant for neutrophils. Chemokines exert their effects by binding to specific receptors on the surface of immune cells, triggering a cascade of intracellular signals that lead to cell migration. Dysregulation of chemokine signaling has been linked to various diseases, including cancer, autoimmune disorders, and infectious diseases. Understanding the role of chemokines in immune responses is essential for developing targeted therapies for these conditions.