biokinetiska

Biokinetiska (biokinetics) is an interdisciplinary field that examines the rates and mechanisms by which biological systems process chemicals, energy, and information. The core concern is how living organisms absorb, distribute, metabolize, and excrete substances (ADME) and how biological processes change over time. Biokinetics relies on experimental data and mathematical modeling to describe concentration–time relationships in tissues and organs.

Common modeling frameworks include compartment models and physiologically based pharmacokinetic (PBPK) models, often integrated with pharmacodynamic (PK/PD) analyses to relate internal exposure to effects. Methods draw from pharmacology, toxicology, physiology, and environmental science, using data from in vitro experiments, animal studies, clinical trials, and exposure assessment.

Applications span drug development, safety assessment, and environmental health, where biokinetics helps predict drug dosing, internal doses from exposures, and the fate of pollutants. In physiology and sports science, biokinetics informs energy metabolism and training adaptations. In South Africa, biokinetics is a health sciences profession known as biokinetics or biokineticism, with practitioners called biokineticists focused on exercise therapy and rehabilitation.

Etymology: from bios (life) and kinetikos (moving); related fields include pharmacokinetics, toxicokinetics, PBPK, PK/PD, and enzyme kinetics.