MPN

MPN most commonly refers to myeloproliferative neoplasm, a group of blood cancers characterized by clonal proliferation of myeloid cells in the bone marrow. Major subtypes include polycythemia vera, essential thrombocythemia, and myelofibrosis. Common driver mutations are JAK2, CALR, and MPL. Symptoms vary and may include fatigue, headaches, splenomegaly, pruritus, or thrombotic events. Diagnosis relies on blood counts, marrow examination, and mutation testing, with risk stratification guiding treatment. Treatments aim to reduce complications and symptoms and may include phlebotomy, cytoreductive therapy, aspirin, or targeted therapies such as JAK inhibitors.

MPN also stands for Manufacturer Part Number, a unique identifier assigned by manufacturers to a specific part or product used for cataloging, procurement, and inventory management. It is often vendor-specific and may be cross-referenced with global trade item numbers (GTINs) like UPC or EAN. Benefits include precise product identification and streamlined sourcing; challenges include lack of universal standardization and potential duplication across manufacturers. Proper data governance and integration with ERP systems improve accuracy and interoperability.